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Gepubliceerd in: Netherlands Heart Journal 12/2017

Open Access 01-09-2017 | Heart Beat

A 46-year-old man with recurrent embolic events

Auteurs: T. Lorjé, N. Barlo, C. L. A. Reichert, W. de Kanter, M. A. Sluman

Gepubliceerd in: Netherlands Heart Journal | Uitgave 12/2017

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A 46-year-old male with advanced adenocarcinoma of the lung presented with venous thrombosis. Despite anticoagulants, he developed a stroke and bowel ischaemia. Echocardiography revealed mobile structures on the mitral valve and at the pulmonary artery origin (Fig. 1). Although treatment for endocarditis and pulmonary embolism was initiated, his condition deteriorated. However, blood cultures remained negative and fever was absent. Non-bacterial thrombotic endocarditis (NBTE) became more likely after establishing progressive malignancy with PET-CT. NBTE is found in 19% of patients with malignancy and thrombotic events, but often not recognised [1]. It is distinguished from infective endocarditis by location of the valvular mass, absence of infection, diffuse thickening of valve leaflets and usual absence of valvular dysfunction [2, 3]. Treatment involves oncological therapy and anticoagulants [4]. Surgery may be considered in progressive valvular disease or recurrent embolism [5]. NBTE should be part of the differential diagnosis in patients with malignancy and thromboembolic complications.
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Netherlands Heart Journal

Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie en de Nederlandse Hartstichting. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...

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Metagegevens
Titel
A 46-year-old man with recurrent embolic events
Auteurs
T. Lorjé
N. Barlo
C. L. A. Reichert
W. de Kanter
M. A. Sluman
Publicatiedatum
01-09-2017
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 12/2017
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/s12471-017-1034-8

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