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2016 | OriginalPaper | Hoofdstuk

10 De normale zwangerschap: foetus en placenta

Auteurs : prof.dr. M.J. Heineman, prof.dr. J.L.H. Evers, prof.dr. L.F.A.G. Massuger, prof.dr. E.A.P. Steegers

Gepubliceerd in: Obstetrie en gynaecologie

Uitgeverij: Bohn Stafleu van Loghum

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Samenvatting

Omdat de foetus zich in de baarmoeder bevindt en daarom alleen maar indirect en intermitterend vervolgd kan worden, vallen de door de zwangerschap geïnduceerde veranderingen bij de moeder meer op dan die bij de foetus. Echter, de moederlijke veranderingen worden bijna volledig door placentahormonen aangestuurd. Deze zorgen ervoor dat het moederlijk organisme zodanig verandert dat het intra-uteriene milieu voor het zich ontwikkelende kind geoptimaliseerd wordt. Hieruit volgt dat uitblijvende moederlijke zwangerschapsveranderingen oorzaak dan wel gevolg kunnen zijn van een suboptimale placentafunctie. Uit recent onderzoek blijken vele zwangerschapscomplicaties al met een gestoorde placentatie vanaf de implantatie te beginnen. Alleen met een beter inzicht in de normale placentaontwikkeling kan men bij zwangerschapscomplicaties die een gevolg zijn van een inadequate placentafunctie, de pathogenese beter leren begrijpen. Met een beter inzicht in de foetale groei en ontwikkeling wordt niet alleen het continuüm met de neonatale ontwikkeling inzichtelijk, maar kunnen ook tijdens de zwangerschap allerlei foetale functies in de context van de nog onvoltooide rijping geplaatst worden, zonder ze meteen op basis van onbegrip als afwijkend te classificeren.
Literatuur
go back to reference Bernirschke K, Kaufmann P. Pathology of the human placenta, 4th ed. New York: Springer, 2000.CrossRef Bernirschke K, Kaufmann P. Pathology of the human placenta, 4th ed. New York: Springer, 2000.CrossRef
go back to reference Burton GJ, Jauniaux E, Watson AL. Maternal arterial connections to the placental intervillous space during first trimester pregnancy: the Boyd collection revisited. Am J Obstet Gynecol. 1999;181:718–24.CrossRefPubMed Burton GJ, Jauniaux E, Watson AL. Maternal arterial connections to the placental intervillous space during first trimester pregnancy: the Boyd collection revisited. Am J Obstet Gynecol. 1999;181:718–24.CrossRefPubMed
go back to reference Carter AM. Comparative studies of placentation and immunology in non-human primates suggest a scenario for the evolution of deep trophoblast invasion and an explanation for human pregnancy disorder2. Reproduction. 2011;141:391–6.CrossRefPubMed Carter AM. Comparative studies of placentation and immunology in non-human primates suggest a scenario for the evolution of deep trophoblast invasion and an explanation for human pregnancy disorder2. Reproduction. 2011;141:391–6.CrossRefPubMed
go back to reference Chamberlain G, Broughton Pipkin F, eds. Clinical physiology in obstetrics. London: Blackwell, 1998. Chamberlain G, Broughton Pipkin F, eds. Clinical physiology in obstetrics. London: Blackwell, 1998.
go back to reference Chard T. Placental synthesis. Clin Obstet Gynaecol. 1986;13:447–67.PubMed Chard T. Placental synthesis. Clin Obstet Gynaecol. 1986;13:447–67.PubMed
go back to reference Creasy RK, Resnik R, eds. Maternal-fetal medicine; Principles and practice, 3rd ed. Philadelphia: Saunders, 1994. Creasy RK, Resnik R, eds. Maternal-fetal medicine; Principles and practice, 3rd ed. Philadelphia: Saunders, 1994.
go back to reference Cunningham FG, McDonald PC, Gant NF, et al. eds. Williams obstetrics, 19th ed. Stamford: Appleton & Lange, 1993. Cunningham FG, McDonald PC, Gant NF, et al. eds. Williams obstetrics, 19th ed. Stamford: Appleton & Lange, 1993.
go back to reference Dunn PM. Variations in fetal growth; some causes, some effects. In: Assche FA van, Robertson WB, eds. Fetal growth retardation. New York: Churchill Livingstone, 1981. p. 79–89. Dunn PM. Variations in fetal growth; some causes, some effects. In: Assche FA van, Robertson WB, eds. Fetal growth retardation. New York: Churchill Livingstone, 1981. p. 79–89.
go back to reference Evers JLH, Heineman MJ, red. Gynaecologie: Een klinische atlas. Utrecht: Bunge, 1994. Evers JLH, Heineman MJ, red. Gynaecologie: Een klinische atlas. Utrecht: Bunge, 1994.
go back to reference Flagg PJ. Treatment of asphyxia in the newborn: Preliminary report of the practical application of modern scientific methods. JAMA. 1928;91:788–91.CrossRef Flagg PJ. Treatment of asphyxia in the newborn: Preliminary report of the practical application of modern scientific methods. JAMA. 1928;91:788–91.CrossRef
go back to reference Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics: Normal & problem pregnancies, 4th ed. New York: Churchill Livingstone, 2002. Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics: Normal & problem pregnancies, 4th ed. New York: Churchill Livingstone, 2002.
go back to reference Gittenberger-de Groot AC, Bartelings MM, Ruiter MC de, Poelman RE. Basics of cardiac development for the understanding of congenital heart malformations. Pediatr Res. 2005;57:169–76.CrossRefPubMed Gittenberger-de Groot AC, Bartelings MM, Ruiter MC de, Poelman RE. Basics of cardiac development for the understanding of congenital heart malformations. Pediatr Res. 2005;57:169–76.CrossRefPubMed
go back to reference Gleicher N, ed. Principles and practice of medical therapy in pregnancy, 2nd ed. Stamford: Appleton & Lange, 1992. Gleicher N, ed. Principles and practice of medical therapy in pregnancy, 2nd ed. Stamford: Appleton & Lange, 1992.
go back to reference Gluckman P, Heyman M, eds. Perinatal and pediatric pathophysiology: A clinical perspective. London: Edward Arnold, 1993. Gluckman P, Heyman M, eds. Perinatal and pediatric pathophysiology: A clinical perspective. London: Edward Arnold, 1993.
go back to reference Harding R, Bocking AD, eds. Fetal growth and development. Cambridge: Cambridge University Press, 2001. Harding R, Bocking AD, eds. Fetal growth and development. Cambridge: Cambridge University Press, 2001.
go back to reference Huppertz B, Peeters LL. Vascular biology in implantation and placentation. Angiogenesis. 2005;8:157–67.CrossRefPubMed Huppertz B, Peeters LL. Vascular biology in implantation and placentation. Angiogenesis. 2005;8:157–67.CrossRefPubMed
go back to reference Jauniaux E, Poston L, Burton GJ. Placental-related disease of pregnancy: involvement of oxidative stress and implications in human evolution. Hum Reprod Update. 2006;12:747–55.CrossRefPubMedPubMedCentral Jauniaux E, Poston L, Burton GJ. Placental-related disease of pregnancy: involvement of oxidative stress and implications in human evolution. Hum Reprod Update. 2006;12:747–55.CrossRefPubMedPubMedCentral
go back to reference Loke YW, King A. Human implantation. Cell biology and immunology. Cambridge: Cambridge University Press, 1995. Loke YW, King A. Human implantation. Cell biology and immunology. Cambridge: Cambridge University Press, 1995.
go back to reference Metcalfe J, Bartels H, Moll W. Gas exchange in the pregnant uterus. Physiol Rev. 1967;47:782–838.CrossRefPubMed Metcalfe J, Bartels H, Moll W. Gas exchange in the pregnant uterus. Physiol Rev. 1967;47:782–838.CrossRefPubMed
go back to reference Milner R. Prenatal growth control. In: Gluckman P, Heyman M, eds. Perinatal and pediatric pathophysiology: A clinical perspective. London: Edward Arnold, 1993. Milner R. Prenatal growth control. In: Gluckman P, Heyman M, eds. Perinatal and pediatric pathophysiology: A clinical perspective. London: Edward Arnold, 1993.
go back to reference Natanielsz P, ed. Reviews in perinatal medicine, vol. 6. New York: Alan R Liss, 1989. Natanielsz P, ed. Reviews in perinatal medicine, vol. 6. New York: Alan R Liss, 1989.
go back to reference Norwitz ER, Schust DJ, Fisher SJ. Implantation and survival of early pregnancy. N Engl J Med. 2001;345:1400–8.CrossRefPubMed Norwitz ER, Schust DJ, Fisher SJ. Implantation and survival of early pregnancy. N Engl J Med. 2001;345:1400–8.CrossRefPubMed
go back to reference Scherjon S, Lashley L, Hoorn ML van der, Claas F. Fetus specific T cell modulation during fertilization, implantation and pregnancy. Placenta. 2011;32(Suppl 4):S291–7.PubMed Scherjon S, Lashley L, Hoorn ML van der, Claas F. Fetus specific T cell modulation during fertilization, implantation and pregnancy. Placenta. 2011;32(Suppl 4):S291–7.PubMed
go back to reference Sparks JW, Girard JR, Battaglia FC. An estimate of the caloric requirements of the human fetus. Biol Neonate. 1980;38:113–9.CrossRefPubMed Sparks JW, Girard JR, Battaglia FC. An estimate of the caloric requirements of the human fetus. Biol Neonate. 1980;38:113–9.CrossRefPubMed
go back to reference Zhou Y, Fisher SJ, Janatpour M, et al. Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion? J Clin Invest. 1997;99:2139–51.CrossRefPubMedPubMedCentral Zhou Y, Fisher SJ, Janatpour M, et al. Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion? J Clin Invest. 1997;99:2139–51.CrossRefPubMedPubMedCentral
go back to reference Ziegler EE, O’Donnell AM, Nelson SE, Fomion SJ. Body composition of the reference fetus. Growth. 1976;40:329–41.PubMed Ziegler EE, O’Donnell AM, Nelson SE, Fomion SJ. Body composition of the reference fetus. Growth. 1976;40:329–41.PubMed
Metagegevens
Titel
10 De normale zwangerschap: foetus en placenta
Auteurs
prof.dr. M.J. Heineman
prof.dr. J.L.H. Evers
prof.dr. L.F.A.G. Massuger
prof.dr. E.A.P. Steegers
Copyright
2016
Uitgeverij
Bohn Stafleu van Loghum
DOI
https://doi.org/10.1007/978-90-368-1191-0_10