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T-Wave Patterns Associated with the Hereditary Long QT Syndrome

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Cardiac Electrophysiology Review

Abstract

Mutations involving 6 different ion-channel genes have been identified in subjects with the hereditaryLong QT Syndrome. These gene mutations result in structural and functional changes in ion-channel proteins withresultant alterations in potassium and sodium repolarization currents that affect the morphologic features ofelectrocardiographic repolarization. This review highlights the genotype-phenotype associations related toventricular repolarization that have been reported in the LQTS literature, with particular focus on ECG T-wavepatterns in LQT1, LQT2, and LQT3 genotypes.

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Authors and Affiliations

  1. Department of Medicine, Division of Cardiology, University of Rochester Medical Center, Rochester, New York, USA

    Arthur J. Moss

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  1. Arthur J. Moss
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Moss, A.J. T-Wave Patterns Associated with the Hereditary Long QT Syndrome. Card Electrophysiol Rev 6, 311–315 (2002). https://doi.org/10.1023/A:1016301730302

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