Skip to main content
Top
Gepubliceerd in: Huisarts en wetenschap 8/2013

01-08-2013 | Nascholing

Endometriumcarcinoom, nieuwe ontwikkelingen

Auteurs: dr. Christianne Lok, dr. Hans Trum

Gepubliceerd in: Huisarts en wetenschap | Uitgave 8/2013

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Samenvatting

Lok C, Trum H. Endometriumcarcinoom, nieuwe ontwikkelingen. Huisarts Wet 2013;56(8):404-7.
Het endometriumcarcinoom is de meest voorkomende maligniteit van de vrouwelijke geslachtsorganen. De ziekte doet zich meestal voor na de menopauze, vaak met abnormaal bloedverlies als eerste symptoom. Als de tumor in een vroeg stadium wordt ontdekt – wat vaak het geval is –, is de prognose gunstig, maar de vijfjaarsoverleving daalt sterk in hogere stadia. De hoeksteen van de behandeling is (laparoscopische) verwijdering van de uterus, de adnexen en eventueel de bekkenlymfeklieren, zo nodig gevolgd door bestraling.
Een patiënte die wegens abnormaal bloedverlies bij de dokter komt, moet altijd gynaecologisch onderzocht worden. Verder is het zaak bedacht te zijn op een genetische predispositie en te vragen of darmkanker en endometriumcarcinomen vaker voorkomen in de familie.
Literatuur
2.
3.
go back to reference Burke W, Petersen G, Lynch P, Botkin J, Daly M, Garber J, et al. Recommendations for follow-up care of individuals with an inherited predisposition to cancer. I. Hereditary nonpolyposis colon cancer. JAMA 1997;277:915-9.PubMedCrossRef Burke W, Petersen G, Lynch P, Botkin J, Daly M, Garber J, et al. Recommendations for follow-up care of individuals with an inherited predisposition to cancer. I. Hereditary nonpolyposis colon cancer. JAMA 1997;277:915-9.PubMedCrossRef
4.
go back to reference Dijkhuizen FP, Mol BW, Brölmann HA, Heintz AP. The accuracy of endometrial sampling in the diagnosis of patients with endometrial carcinoma and hyperplasia: a meta-analysis. Cancer 2000;89:1765-72.PubMedCrossRef Dijkhuizen FP, Mol BW, Brölmann HA, Heintz AP. The accuracy of endometrial sampling in the diagnosis of patients with endometrial carcinoma and hyperplasia: a meta-analysis. Cancer 2000;89:1765-72.PubMedCrossRef
6.
go back to reference Obermair A, Janda M, Baker J, Kondalsamy-Chennakesavan S, Brand A, Hogg R, et al. Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: results from a randomised controlled trial. Eur J Cancer 2012;48:1147-53.PubMedCrossRef Obermair A, Janda M, Baker J, Kondalsamy-Chennakesavan S, Brand A, Hogg R, et al. Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: results from a randomised controlled trial. Eur J Cancer 2012;48:1147-53.PubMedCrossRef
7.
go back to reference Galaal K, Bryant A, Fisher AD, Al-Khaduri M, Kew F, Lopes AD. Laparoscopy versus laparotomy for the management of early stage endometrial cancer. Cochrane Database Syst Rev 2012;(9):CD006655. Galaal K, Bryant A, Fisher AD, Al-Khaduri M, Kew F, Lopes AD. Laparoscopy versus laparotomy for the management of early stage endometrial cancer. Cochrane Database Syst Rev 2012;(9):CD006655.
8.
go back to reference Bijen CB, Vermeulen KM, Mourits MJ, Arts HJ, Ter Brugge HG, Van der Sijde R, et al. Cost effectiveness of laparoscopy versus laparotomy in early stage endometrial cancer: a randomised trial. Gynecol Oncol 2011;121:76-82.PubMedCrossRef Bijen CB, Vermeulen KM, Mourits MJ, Arts HJ, Ter Brugge HG, Van der Sijde R, et al. Cost effectiveness of laparoscopy versus laparotomy in early stage endometrial cancer: a randomised trial. Gynecol Oncol 2011;121:76-82.PubMedCrossRef
9.
go back to reference Bijen CB, De Bock GH, Vermeulen KM, Arts HJ, Ter Brugge HG, Van der Sijde R, et al.. Laparoscopic hysterectomy is preferred over laparotomy in early endometrial cancer patients, however not cost effective in the very obese. Eur J Cancer 2011;47:2158-65.PubMedCrossRef Bijen CB, De Bock GH, Vermeulen KM, Arts HJ, Ter Brugge HG, Van der Sijde R, et al.. Laparoscopic hysterectomy is preferred over laparotomy in early endometrial cancer patients, however not cost effective in the very obese. Eur J Cancer 2011;47:2158-65.PubMedCrossRef
10.
go back to reference Janda M, Gebski V, Brand A, Hogg R, Jobling TW, Land R, et al. Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): a randomised trial. Lancet Oncol. 2010;11:772-80.PubMedCrossRef Janda M, Gebski V, Brand A, Hogg R, Jobling TW, Land R, et al. Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): a randomised trial. Lancet Oncol. 2010;11:772-80.PubMedCrossRef
11.
go back to reference Kondalsamy-Chennakesavan S, Janda M, Gebski V, Baker J, Brand A, Hogg R, et al. Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: results from a randomised controlled trial. Eur J Cancer 2012;48:2155-62.PubMedCrossRef Kondalsamy-Chennakesavan S, Janda M, Gebski V, Baker J, Brand A, Hogg R, et al. Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: results from a randomised controlled trial. Eur J Cancer 2012;48:2155-62.PubMedCrossRef
12.
go back to reference May K, Bryant A, Dickinson HO, Kehoe S, Morrison J. Lymphadenectomy for the management of endometrial cancer. Cochrane Database Syst Rev 2010;(1):CD007585. May K, Bryant A, Dickinson HO, Kehoe S, Morrison J. Lymphadenectomy for the management of endometrial cancer. Cochrane Database Syst Rev 2010;(1):CD007585.
13.
go back to reference Walker JL, Piedmonte MR, Spirtos NM, Eisenkop SM, Schlaerth JB, Mannel RS, et al. Recurrence and survival after random assignment to laparoscopy versus laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group LAP2 Study. J Clin Oncol 2012;30:695-700.PubMedCrossRef Walker JL, Piedmonte MR, Spirtos NM, Eisenkop SM, Schlaerth JB, Mannel RS, et al. Recurrence and survival after random assignment to laparoscopy versus laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group LAP2 Study. J Clin Oncol 2012;30:695-700.PubMedCrossRef
Metagegevens
Titel
Endometriumcarcinoom, nieuwe ontwikkelingen
Auteurs
dr. Christianne Lok
dr. Hans Trum
Publicatiedatum
01-08-2013
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Huisarts en wetenschap / Uitgave 8/2013
Print ISSN: 0018-7070
Elektronisch ISSN: 1876-5912
DOI
https://doi.org/10.1007/s12445-013-0211-2

Andere artikelen Uitgave 8/2013

Huisarts en wetenschap 8/2013 Naar de uitgave

Intermezzo

Krakers