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Effect of Exercise and Pharmacologic Interventions on Coronary Collateral Blood Flow

  • Chapter
Collateral Circulation

Abstract

Coronary artery occlusion results in remarkably rapid development of an effective intercoronary collateral circulation. If occlusion proceeds gradually, sufficient collateral vessel recruitment and growth may occur to allow progression to total arterial occlusion with little or no infarction of the dependent myocardium. In this situation the collateral vessels are able to provide adequate arterial inflow to maintain myocardial integrity during resting conditions, but the ability to augment blood flow in response to exercise or other stress may be limited and develop only gradually. This chapter will consider studies of the coronary vascular system in the intact heart which contains a region of collateral dependent myocardium. Emphasis will be placed on studies in which the response of the coronary collateral system is integrated into the overall response of the heart to exercise.

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References

  1. Litvak J, Siderides LE, Vineberg AM (1957) Am Heart J 53:505–518

    Article  PubMed  CAS  Google Scholar 

  2. Fedor JM, Rembert JC, McIntosh DM, Greenfield JC (1980) Circ Res 46:214–220

    Article  PubMed  CAS  Google Scholar 

  3. Bache RJ, Schwartz JS (1983) Am J Physiol 245:H131–H138

    PubMed  CAS  Google Scholar 

  4. Lambert PR, Hess DS, and Bache RJ (1977) J Clin Invest 59:1–7

    Article  CAS  Google Scholar 

  5. Roth DM, Maruoka Y, Rogers J, White FC, Longhurst JC, Bloor CM (1987) Am J Physiol 253:H1279–H1288

    PubMed  CAS  Google Scholar 

  6. White FC, Roth DM, Bloor CM (1989) Basic Res Cardiol 84:42–54

    Article  PubMed  CAS  Google Scholar 

  7. Ball RM and Bache RJ (1976) Circ Res 38:60–66

    Article  PubMed  CAS  Google Scholar 

  8. Sanders TM, White FC, Peterson TM, Bloor DM (1978) Am J Physiol 235:H601–H609

    PubMed  CAS  Google Scholar 

  9. Longhurst JC, Motohara S, Atkins JM, Ordway GA (1985) J Appl Physiol 59:392–400

    PubMed  CAS  Google Scholar 

  10. Harrison DG, Chilian WM, Marcus ML (1986) Circ Res 59:133–142

    Article  PubMed  CAS  Google Scholar 

  11. Hautamaa PV, Dai XZ, Homans DC, Bache RJ (1989) Am J Physiol 256:H890–H897

    PubMed  CAS  Google Scholar 

  12. Katusic ZS, Shepherd JT, Vanhoutte PM (1984) Circ Res 55:575–579

    Article  PubMed  CAS  Google Scholar 

  13. Foreman BW, Dai XZ, Bache RJ (1991) Circ Res 69:657–664

    Article  PubMed  CAS  Google Scholar 

  14. Franklin D, McKown D, McKown M, Hastley J, Caldwell M (1981) Fed Proc 40:339

    Google Scholar 

  15. Patterson RE, Kirk ES (1980) Circ Res 47:108–116

    Article  PubMed  CAS  Google Scholar 

  16. Sellke FW, Quillen JE, Brooks LA, Harrison DG (1990) Circulation 81:1938–1947

    Article  PubMed  CAS  Google Scholar 

  17. Waeber B, Schaller MD, Nussberger J, Bussien JP, Hotbauer KG, Brunner HR (1984) Am J Physiol 247:H895–H901

    PubMed  CAS  Google Scholar 

  18. Goetz KL, Wang BC, Sundet WD (1984) J Physiol (Paris) 79:440–445

    CAS  Google Scholar 

  19. Schaper W, Remijsen P, Xhonneux R (1969) Z Kreislaufforsch 58:904–909

    PubMed  CAS  Google Scholar 

  20. Rivas R, Cobb FR, Bache RJ, Greenfield JC Jr (1976) Circ Res 38:439–447

    Article  PubMed  CAS  Google Scholar 

  21. Hess DS, Bache RJ (1980) Circ Res 47:59–68

    Article  PubMed  CAS  Google Scholar 

  22. Herzog CA, Aeppli DP, Bache RJ (1984) J Am Coll Cardiol 4:1174–1183

    Article  PubMed  CAS  Google Scholar 

  23. Herzog CA, Dai X, Bache RJ (1991) Am J Physiol 261:H280–H286

    PubMed  CAS  Google Scholar 

  24. Fedele FA, Gewirtz H, Capone RJ, Sharaf B, Most AS (1988) Circulation 78:729–735

    Article  PubMed  CAS  Google Scholar 

  25. Feldman RD, Christy JP, Paul ST, Harrison DG (1989) Am J Physiol 257:H1634–H1639

    PubMed  CAS  Google Scholar 

  26. Maruoka Y, McKirnan MD, Engler RL, Longhurst JC (1987) Am J Physiol 253:H582–H590

    PubMed  CAS  Google Scholar 

  27. Gwirtz, PA, Overn SP, Mass JH, Jones CE (1986) Am J Physiol 250:H1117–H1126

    PubMed  CAS  Google Scholar 

  28. Bache RJ, Dai XZ, Herzog CA, Schwartz JS (1987) Circ Res 61:II-36-II-41

    Google Scholar 

  29. Buffington CW, Feigl EO (1981) Circ Res 48:416–423

    Article  PubMed  CAS  Google Scholar 

  30. Jones CE, Liang IY, Maulsby MR (1986) J Pharmacol Exp Ther 236:204–211

    PubMed  CAS  Google Scholar 

  31. Laxson DD, Dai X, Homans DC, Bache RJ (1989) Circ Res 65:1688–1697

    Article  PubMed  CAS  Google Scholar 

  32. Aversano T, Becker LC (1985) Am J Physiol 248:H403–H411

    PubMed  CAS  Google Scholar 

  33. Laxson DD, Homans DX, Homans DC, Bache RJ (1992) Circulation 85:313–322

    Article  PubMed  CAS  Google Scholar 

  34. Seitelberger R, Guth BD, Heusch G, Lee JD, Katayama K, Ross J (1988) Circ Res 62:436–442

    Article  PubMed  CAS  Google Scholar 

  35. Fam WM, McGregor M (1964) Circ Res 15:355–365

    Article  PubMed  CAS  Google Scholar 

  36. Becker LC (1976) J Clin Invest 58:1287

    Article  PubMed  CAS  Google Scholar 

  37. Bache RJ (1978) Circulation 57:557–562

    Article  PubMed  CAS  Google Scholar 

  38. Foreman BW, Dai X-Z, Homans DC, Laxson DD, Bache RJ (1989) Circ Res 65:1671–1678

    Article  PubMed  CAS  Google Scholar 

  39. Rapoport RM, Waldman SA, Ginsburg R, Molina CR, Murad F (1987) J Cardiovasc Pharmacol 10:82–89

    Article  PubMed  CAS  Google Scholar 

  40. Winquist RJ, Faison EP, Waldman SA, Schwartz K, Murad F, Rapoport RM (1984) Proc Natl Acad Sci USA 81:7661–7664

    Article  PubMed  CAS  Google Scholar 

  41. Quebbemann BB, Pavek T, Ya X, Bache RJ (1990) Circulation 82:III-420

    Google Scholar 

  42. Heyndrickx GR, Boettcher DH, Vatner SF (1976) Am J Physiol 231:1579

    PubMed  CAS  Google Scholar 

  43. Bache RJ, Foreman B, Hautamaa PV (1991) Am J Physiol 261:H1019–H1025

    PubMed  CAS  Google Scholar 

  44. Wright L, Homans DC, Laxson DD, Dai X-Z, Bache RJ (1992) J Am Coll Cardiol 19:687–693

    Article  PubMed  CAS  Google Scholar 

  45. Golino P, Ashton JH, Buja LM, Rosolowsky M, Taylor AL, McNatt J, Campbell WB, Willerson JT (1989) Circulation 79:154–166

    Article  PubMed  CAS  Google Scholar 

  46. Dai X, Bache R (1984) Am J Physiol 247:H452–H458

    PubMed  CAS  Google Scholar 

  47. Schaper J, Koenig R, Franz D, Schaper W (1976) Virchows Arch A Path Anat Histol 370:193–205

    Article  CAS  Google Scholar 

  48. Altman J, Dulas D, Bache RJ (1991) Circulation 84:II-96

    Google Scholar 

  49. Furchgott RF, Zawadski JV (1980) Nature 288:373–376

    Article  PubMed  CAS  Google Scholar 

  50. Ignarro LJ, Byrns RE, Buga GM, Wood KS (1987) Circ Res 61:866–879

    Article  PubMed  CAS  Google Scholar 

  51. Bassenge E, Heusch G (1990) Rev Phys Biochem Pharmacol 116:77–125

    CAS  Google Scholar 

  52. Angus JA, Ward JE, Smolich JJ, McPherson GA (1991) Circ Res 69:1340–1352

    Article  PubMed  CAS  Google Scholar 

  53. Flynn NM, Kenny D, Pelc LR, Warltier DC, Bosnjak ZJ, Kampine JP (1991) Am J Physiol 261:H1797–H1782

    PubMed  CAS  Google Scholar 

  54. Altman J, Dulas D, Laxson DD, Homans DC, Bache RJ (1991) Circulation 84: II-97

    Google Scholar 

  55. Canty JM Jr, Klocke FJ (1985) Circulation 71:370–377

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA

    Robert J. Bache

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  1. Robert J. Bache
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Editors and Affiliations

  1. Department of Experimental Cardiology, Max-Planck-Institute, Benekestrasse 2, D-6350, Bad Nauheim, F. R. Germany

    Wolfgang Schaper M.D., Ph.D.  & Jutta Schaper M.D., Ph.D.  & 

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© 1992 Springer Science+Business Media New York

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Bache, R.J. (1992). Effect of Exercise and Pharmacologic Interventions on Coronary Collateral Blood Flow. In: Schaper, W., Schaper, J. (eds) Collateral Circulation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3092-3_9

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  • DOI: https://doi.org/10.1007/978-1-4615-3092-3_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6351-4

  • Online ISBN: 978-1-4615-3092-3

  • eBook Packages: Springer Book Archive

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